Medicine Box Presents…

The Mushroom Microdosing Manifesto

A Brief Guidebook for Your Microdosing Journey

Since the publication of The Psychedelic Explorer’s Guide in 2011, the once-underground psychedelic medicine practice of microdosing - which involves taking subperceptual doses of psychedelic medicines such as psilocybin intermittently over extended periods of time - has exploded across the globe.

  • Practitioners in 69 countries have responded to an initial survey conducted by Explorer's Guide author James Fadiman.


  • A survey of 8000 microdosers published in Nature found that those who microdosed to treat mental health issues scored lower on measurements related to stress, anxiety, and depression compared to non-microdosers also polled within the study.


  • Participants in another online survey reported reduced use of alcohol, caffeine, tobacco, and other illicit drugs after microdosing.

So the potential gains from microdosing could be immense.


But how does one microdose? Who should do it, and who should avoid it? How long should you do it, and how do you know if yours is a true microdose? How does one get started, and how does one reap the most benefits from it?


All of these questions and more are answered in THE MUSHROOM MICRODOSING MANIFESTO.


In this book, you’ll learn...


  • The 8 resolutions of the mushroom microdosing manifesto
  • How to use the Medicine Box mushroom microdosing protocol, along with our Mind's Eye supplement
  • How to implement microdosing as a tool to aid recovery from substances or destructive habits
  • Microdosing's potential pitfalls, and how to avoid them
Fill out our survey and start your microdosing journey today!

Interested in enhancing your microdosing protocol?


Then see how Medicine Box’s Mind’s Eye nootropic microdosing supplement stacks up!


Harmonize your cognitive function with clarity, focus, intuitive flow and memory support with this synergistic blend of botanicals, adaptogens and essential nutrients.


We’ve created a mixture of shroomies (fruiting bodies only), herbs and minerals (only the best in small batches we can find) to give your brain an extra boost during your dosing days and added momentum on your rest days.


  • Ashwaganda and holy basil to calm the mind and reduce nervous tension
  • Seamoss as a neuroprotective that supports thyroid, energy recovery, and immune health
  • Turmeric as an antioxidant and anti-inflammatory; combats degenerative processes in the brain
  • Brahmi for mental clarity, memory improvement, greater tranquility and antioxidant activity
  • Lion's Mane for neurogenesis
  • Cordyceps for an energy boost
  • Agarikon and Reishi for anti-inflammatory/immunomodulatory superpowers
  • Chaga for heart, health, and optimal blood sugar
  • Turkery Tail as a gut enhancing probiotic
  • Niacin and Magnesium L-Threonate for neuronal support and plasticity

Now available in our Shopify store!